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Primenjuje se i kao dodatna terapija tokom endoskopije, hirurških intervencija, intervencija u stomatologiji i u radiologiji.

Lekovi iz grupe benzodiazepina se ne smeju primenjivati samostalno kod depresije ili anksioznosti udružene sa depresijom, jer u tom slučaju mogu doprineti razvoju suicidalnih misli (misli o samoubistvu).

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